| 11:29 PM | Saturday Night Live: Anne Hathaway hosts; the Killers perform. |
| 1:02 AM | Local Programming |
| 1:32 AM | Access Hollywood: The hottest entertainment news of the week. |
| 2:02 AM | Poker After Dark: Top poker professionals compete for $120,000 from the Las Vegas strip. |
| 3:02 AM | Strikeforce on NBC: Mixed martial arts competition. |
| 3:30 AM | Access Hollywood: The hottest entertainment news of the week. |
| 4:30 AM | EXTRA: Perez Hilton; Heather Locklear's new DUI shocker; Lindsay Lohan. |
| 5:30 AM | Hispanics Today: Bataan death march survivor; roofing; business expo. |
| 6:00 AM | Local Programming |
| 9:00 AM | Today: Author Blair Underwood (``In the Night of the Heat''); saving on home appliances. |
| 10:00 AM | The Chris Matthews Show: Guests discuss whether Barack Obama has generated momentum. |
| 10:30 AM | Meet the Press: Democratic strategist Paul Begala and GOP strategist Mike Murphy. |
| 11:30 AM | Wall Street Journal Report With Maria Bartiromo: Bill Gross and Bob Doll discuss the rescue plan. |
| 12:00 PM | Access Hollywood: The hottest entertainment news of the week. |
| 1:00 PM | Local Programming |
| 2:00 PM | Allure Backstage: 8 Top Beauty Trends Fall 2008: Top designers, models and makeup artists. |
| 2:30 PM | CORR Off Road Racing: From Chula Vista, Calif. |
| 4:00 PM | Local Programming |
| 6:30 PM | NBC Nightly News: The latest world and national news. |
| 7:00 PM | Football Night in America: With Bob Costas, Cris Collinsworth, Jerome Bettis and Tiki Barber. |
| 8:15 PM | NFL Football - Pittsburgh Steelers at Jacksonville Jaguars : The Jaguars look for a third straight win when they play host to the Steelers in a key AFC matchup. |
| 11:30 PM | Local Programming |