| Ted Danson | ... | Sam Malone (270 episodes, 1982-1993) |
 | Rhea Perlman | ... | Carla Tortelli / ... (270 episodes, 1982-1993) |
| George Wendt | ... | Norm Peterson (270 episodes, 1982-1993) |
| John Ratzenberger | ... | Cliff Clavin (268 episodes, 1982-1993) |
| Kelsey Grammer | ... | Dr. Frasier Crane (201 episodes, 1984-1993) |
| Woody Harrelson | ... | Woody Boyd (198 episodes, 1985-1993) |
| Kirstie Alley | ... | Rebecca Howe (147 episodes, 1987-1993) |
| Shelley Long | ... | Diane Chambers (123 episodes, 1982-1993) |
| Bebe Neuwirth | ... | Dr. Lilith Sternin-Crane / ... (78 episodes, 1986-1993) |
| Nicholas Colasanto | ... | Ernie 'Coach' Pantusso (70 episodes, 1982-1985) |
| Paul Willson | ... | Paul Krapence / ... (55 episodes, 1983-1993) |
| Peter Schreiner | ... | Pete (40 episodes, 1987-1993) |
| Alan Koss | ... | Alan / ... (40 episodes, 1983-1993) |
| Al Rosen | ... | Al (38 episodes, 1984-1989) |
| Tim Cunningham | ... | Tim / ... (37 episodes, 1982-1993) |
| Steve Giannelli | ... | Steve / ... (28 episodes, 1984-1993) |
| Philip Perlman | ... | Phil (27 episodes, 1986-1993) |
| Jackie Swanson | ... | Kelly Gaines / ... (24 episodes, 1989-1993) |
| Roger Rees | ... | Robin Colcord (17 episodes, 1989-1993) |
| Hugh Maguire | ... | Hugh (15 episodes, 1987-1988) |
| Keene Curtis | ... | John Allen Hill (15 episodes, 1990-1993) |
| Thomas Babson | ... | Tom / ... (11 episodes, 1982-1988) |
| Larry Harpel | ... | Larry / ... (11 episodes, 1984-1987) |
| Paul Vaughn | ... | Paul / ... (10 episodes, 1982-1983) |
| Tony DiBenedetto | ... | Tony (9 episodes, 1989-1991) |
| Mark Arnott | ... | Mark (9 episodes, 1987-1990) |
| Jay Thomas | ... | Eddie LeBec (9 episodes, 1987-1989) |
| Jack Knight | ... | Jack (8 episodes, 1982-1983) |
| Michael Holden | ... | Joe / ... (8 episodes, 1986-1992) |
| Richard Doyle | ... | Mr. Walter Gaines (8 episodes, 1989-1993) |
| Frances Sternhagen | ... | Esther Clavin (7 episodes, 1986-1993) |
| Harry Anderson | ... | Harry 'The Hat' Gittes (6 episodes, 1982-1993) |
| Dan Hedaya | ... | Nick Tortelli (6 episodes, 1984-1993) |
| Jean Kasem | ... | Loretta Tortelli (6 episodes, 1984-1993) |
| Tom Skerritt | ... | Evan Drake (6 episodes, 1987-1988) |
| Christopher Graves | ... | Frederick Crane (6 episodes, 1991-1993) |
| Kevin Graves | ... | Frederick Crane (6 episodes, 1991-1993) |
| Bernadette Birkett | ... | Vera Peterson / ... (5 episodes, 1984-1993) |
| Amanda Ingber | ... | Annie Tortelli / ... (5 episodes, 1985-1988) |
| Timothy Williams | ... | Anthony Tortelli (5 episodes, 1985-1988) |
| Barry Zajac | ... | Barry (5 episodes, 1990-1993) |
| Anthony Cistaro | ... | Henrí (5 episodes, 1990-1992) |
| Fred Dryer | ... | Dave Richards (4 episodes, 1982-1987) |
| Jacqueline Cassell | ... | Customer #1 / ... (4 episodes, 1982-1986) |
| Derek McGrath | ... | Andy Schroeder (4 episodes, 1983-1992) |
| Eric Christmas | ... | Father Barry (4 episodes, 1988-1991) |
| Annie Golden | ... | Margaret 'Maggie' O'Keefe (4 episodes, 1989-1992) |
| Robert Machray | ... | Fire Marshal Dobbins (4 episodes, 1990-1993) |
| Josh Lozoff | ... | Gino Tortelli (4 episodes, 1991-1993) |
| Michael McGuire | ... | Prof. Sumner Sloan (3 episodes, 1982-1987) |
| Raye Birk | ... | Walt Twitchell (3 episodes, 1985-1992) |
| Joel Polis | ... | Gary (3 episodes, 1985-1990) |
| David Paymer | ... | Phil Schumacher / ... (3 episodes, 1985-1986) |
| Doris Grau | ... | Corinne (3 episodes, 1986-1987) |
| Kate Mulgrew | ... | Janet Eldridge (3 episodes, 1986) |
| Catherine MacNeal | ... | Joanne / ... (3 episodes, 1987-1990) |
| Robert Desiderio | ... | Gary (3 episodes, 1988-1993) |
| Jarrett Lennon | ... | Ludlow Tortelli (3 episodes, 1989-1992) |
| Webster Williams | ... | Miles (3 episodes, 1989-1990) |
| Danny Kramer | ... | Elvis LeBec (3 episodes, 1991-1992) |
| Thomas Tulak | ... | Jesse LeBec (3 episodes, 1991-1992) |
| Randy Pelish | ... | Customer / ... (2 episodes, 1990-1991) |
| Stanley Bennett Clay | ... | Albert / ... (2 episodes, 1990-1991) |
| Teddy Bergeron | ... | Man #1 (2 episodes, 1982) |
| Lois De Banzie | ... | Lady #1 / ... (2 episodes, 1983-1985) |
| Dean Dittman | ... | Harrison Fiedler (2 episodes, 1983-1985) |
| Kenneth Tigar | ... | Dr. Lowell Greenspon / ... (2 episodes, 1983-1985) |
| Elizabeth Hill | ... | Female Customer #1 / ... (2 episodes, 1983-1984) |
| Duncan Ross | ... | Boggs (2 episodes, 1983-1984) |
| Mark King | ... | Marshall Lipton (2 episodes, 1983) |
| Herb Mitchell | ... | Mort Sherwin / ... (2 episodes, 1983) |
| Brian Burt | ... | Customer #2 (2 episodes, 1984) |
| Christopher Carroll | ... | Ed (2 episodes, 1984) |
| Bette Ford | ... | Irene Blanchard (2 episodes, 1984) |
| Christopher Lloyd | ... | Phillip Semenko (2 episodes, 1984) |
| Ellen Regan | ... | Sue Blanchard (2 episodes, 1984) |
| Sam Scarber | ... | Lewis (2 episodes, 1984) |
| Carolyn Ann Clark | ... | April / ... (2 episodes, 1985-1986) |
| Amanda Wyss | ... | Beth Curtis / ... (2 episodes, 1985-1986) |
| Ernie Sabella | ... | Santo Carbone / ... (2 episodes, 1985) |
| Douglas Anderson | ... | 139th Street Quartet / ... (2 episodes, 1986-1989) |
| James Kline | ... | 139th Street Quartet / ... (2 episodes, 1986-1989) |
| Peter Neushul | ... | 139th Street Quartet / ... (2 episodes, 1986-1989) |
| Lawrence Lott | ... | Reporter #2 / ... (2 episodes, 1986) |
| J.J. Wall | ... | Customer / ... (2 episodes, 1986) |
| Max Wright | ... | Jim Fleener (2 episodes, 1986) |
| Sharon Barr | ... | Connie / ... (2 episodes, 1987-1993) |
| Janet Brandt | ... | Mama LeBec (2 episodes, 1987) |
| Greg Collins | ... | Exterminator #1 / ... (2 episodes, 1988-1989) |
| Gerald Hiken | ... | Dennis (2 episodes, 1988) |
| Vincent Howard | ... | Heppel (2 episodes, 1988) |
| Alex Nevil | ... | Martin Teal (2 episodes, 1988) |
| George Shannon | ... | Burns (2 episodes, 1988) |
| Jeffrey Richman | ... | Lee Bradken (2 episodes, 1989-1991) |
| Kevin Conroy | ... | Darryl Mead (2 episodes, 1989-1990) |
| Anne De Salvo | ... | Gloria LeBec (2 episodes, 1989-1990) |
| Gilbert Girion | ... | Will (2 episodes, 1989-1990) |
| Vaughn Armstrong | ... | Mr. Osborn / ... (2 episodes, 1989) |
| Fredric Cook | ... | Detective McGuiness (2 episodes, 1989) |
| Michael Currie | ... | Mr. Sheridan (2 episodes, 1989) |
| Cynthia Stevenson | ... | Doris (2 episodes, 1989) |
| Diedrich Bader | ... | Paul / ... (2 episodes, 1990-1991) |
| Georgia Brown | ... | Madame Lazora (2 episodes, 1990-1991) |
| Phyllis Katz | ... | Brenda Balzak / ... (2 episodes, 1990-1991) |
| Kevin McHale | ... | Himself (2 episodes, 1990-1991) |
| Jonathan McMurtry | ... | Jim Montgomery (2 episodes, 1990) |
| Bill Medley | ... | Himself (2 episodes, 1990) |
| James Nardini | ... | James (2 episodes, 1990) |
| Leah Remini | ... | Serafina Tortelli (2 episodes, 1991-1993) |
| Peter Kevoian | ... | Fireman / ... (2 episodes, 1991-1992) |
| Sabrina Wiener | ... | Lucinda (2 episodes, 1991-1992) |
| Robert Cornthwaite | ... | Hives (2 episodes, 1992-1993) |
| Peter Vogt | ... | Dr. Louis Pascal (2 episodes, 1992-1993) |
| Larry Brandenburg | ... | Cop (2 episodes, 1992) |
| Lenny Citrano | ... | Customer #1 / ... (2 episodes, 1992) |
| Peter Keleghan | ... | Kirby (2 episodes, 1992) |
| Tom Berenger | ... | Don Santry (2 episodes, 1993) |
|
| James Castle | .... | title designer (29 episodes, 1982-1990) |
| Bruce Bryant | .... | title designer (28 episodes, 1982-1990) |
| Diane Overdiek | .... | assistant to executive producer / assistant to executive producers (28 episodes, 1982-1987) |
| Susie Johnson | .... | production coordinator (25 episodes, 1991-1992) |
| Rosie Dean | .... | production coordinator (25 episodes, 1992-1993) |
| David Lloyd | .... | executive script consultant / creative consultant (24 episodes, 1982-1990) |
| Gil Clasen | .... | technical coordinator (22 episodes, 1982-1985) |
| Nancy Koppang | .... | assistant to executive producer (18 episodes, 1982-1983) |
| Glen Miller | .... | assistant to executive producer (18 episodes, 1982-1983) |
| Marsha Nadler | .... | assistant to executive producer (17 episodes, 1982-1984) |
| Lana Repp-Lewis | .... | assistant to executive producer (17 episodes, 1982-1983) |
| Scott Spencer Gordon | .... | assistant to executive producer (16 episodes, 1982-1983) |
| Alison E. Wrigley | .... | assistant to executive producer (16 episodes, 1982-1983) |
| Tony Colvin | .... | assistant to executive producer (14 episodes, 1982-1984) |
| Sharon Black | .... | assistant to executive producer (13 episodes, 1982-1983) |
| Gabrielle James | .... | script supervisor (13 episodes, 1983-1991) |
| Rick Beren | .... | assistant to executive producer / technical coordinator / ... (12 episodes, 1984-1990) |
| Sue Herring | .... | assistant to executive producer / assistant to executive producers / ... (12 episodes, 1984-1990) |
| Christine Connor | .... | assistant to executive producer / assistant: Glen & Les Charles (11 episodes, 1984-1990) |
| Mary Fukuto | .... | assistant to executive producer / assistant to executive producers (11 episodes, 1984-1987) |
| Sonny P. Filippini | .... | script supervisor (10 episodes, 1982-1983) |
| Peter Chakos | .... | assistant to executive producer / assistant: Glen & Les Charles (7 episodes, 1985-1990) |
| Carol Navratil | .... | assistant to executive producer / assistant: Glen & Les Charles (7 episodes, 1986-1990) |
| Barry Zajac | .... | assistant to executive producer / assistant: Glen & Les Charles (7 episodes, 1986-1990) |
| Sheila Guthrie | .... | assistant to executive producer (6 episodes, 1983-1987) |
| Bill Steinkellner | .... | executive story consultant (6 episodes, 1985-1987) |
| Cherie Steinkellner | .... | executive story consultant (6 episodes, 1985-1987) |
| Bob Ellison | .... | executive script consultant (6 episodes, 1986-1990) |
| David Reid | .... | assistant to executive producer (6 episodes, 1986-1987) |
| Danielle Veerman | .... | assistant to executive producer (6 episodes, 1986-1987) |
| David Angell | .... | executive story editor (5 episodes, 1983-1985) |
| Doris Grau | .... | script supervisor (5 episodes, 1983-1985) |
| Heide Perlman | .... | executive story consultant / executive script consultant (5 episodes, 1983-1985) |
| Leslie Brenner | .... | assistant to executive producer / assistant to executive producers (5 episodes, 1984-1986) |
| Rebecca Helm | .... | assistant to executive producer / assistant to executive producers (5 episodes, 1984-1986) |
| Debra Wanderer | .... | assistant to executive producer / assistant to executive producers (5 episodes, 1984-1985) |
| Bill Fraley | .... | technical coordinator (5 episodes, 1986-1987) |
| Lori A. Moneymaker | .... | assistant to executive producer (5 episodes, 1986-1987) |
| Tom Tenowich | .... | creative consultant (5 episodes, 1986-1987) |
| Donna Wheeler | .... | assistant to executive producer (4 episodes, 1982) |
| Penelope Franks | .... | assistant to executive producer (4 episodes, 1983) |
| Danny Lipsius | .... | assistant to executive producer (4 episodes, 1983) |
| Geraldine Leder | .... | assistant to executive producer (4 episodes, 1984-1985) |
| Mary Ann Leslie | .... | assistant to executive producer / assistant to executive producers (4 episodes, 1984-1985) |
| Cary Matsumura | .... | assistant to executive producer (4 episodes, 1984-1985) |
| Janet Allen | .... | assistant to executive producer (3 episodes, 1983) |
| Michael Zito | .... | assistant to executive producer (3 episodes, 1984) |
| Land Courtney Hay | .... | assistant to executive producer (3 episodes, 1986) |
| Jeff Abugov | .... | story editor (3 episodes, 1987) |
| Phoef Sutton | .... | story editor (3 episodes, 1987) |
| Mark Burman | .... | assistant to executive producer (2 episodes, 1983) |
| J.W. Smith | .... | assistant to executive producer (2 episodes, 1983) |
| Janet Leahy | .... | story editor (2 episodes, 1986-1987) |
| Tonya Cannon | .... | assistant to executive producer (2 episodes, 1986) |
| Penny Segal | .... | assistant to executive producer (2 episodes, 1986) |
| Benzion Bergman | .... | assistant to executive producer (2 episodes, 1987) |
| Rachelle Ricks | .... | assistant to executive producer (1 episode, 1985-1986) |
| Mark Nasser | .... | assistant: Glen & Les Charles (1 episode, 1987-1991) |
| Carol Johnsen | .... | title designer (1 episode, 1990) |
|
| Marcia Friedman | .... | assistant to executive producer (unknown episodes, 1983-1984) |
| Brian H. Sato | .... | assistant to executive producer (unknown episodes, 1983-1984) |
| Todd Stevens | .... | assistant to executive producer (unknown episodes, 1983-1984) |
| Lori Kay Wilson | .... | assistant to executive producer (unknown episodes, 1983) |
| Richard P. Solomon | .... | assistant to executive producer (unknown episodes, 1984) |
| Margi Lintz | .... | assistant to executive producer (unknown episodes, 1985-1986) |
| Alexis Kasperavicius | .... | production assistant (unknown episodes, 1986) |
| Hala Gabriel | .... | production accountant (unknown episodes, 1992-1993) |
| Joan Carey | .... | stand-in (unknown episodes) |
| Marilyn A. Dustin | .... | assistant to executive producer (unknown episodes) |
| Ahuva Fogel | .... | assistant to executive producer (unknown episodes) |
| Marni Gaylord | .... | assistant to executive producer (unknown episodes) |
| Nicholas Grad | .... | assistant to executive producer (unknown episodes) |
| Georgyne LaLone | .... | production coordinator (unknown episodes) |
| Dominic Jack Pizzo Sr. | .... | production assistant (unknown episodes) |
| |
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